Prostate Knowledge Blog

Join in the conversation about common issues, breaking news, and research related to prostate health.

By Patrick Skerrett When the SELECT trial started in 2001, there were high hopes it would prove that taking vitamin E or selenium could help prevent prostate cancer. The newest results from the trial show just the opposite—that taking selenium or vitamin E can actually increase the odds of developing prostate cancer. Bottom line: men […]

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When it comes to prostate trouble, the lion’s share of attention goes to prostate cancer and an enlarged prostate. A third condition, prostatitis, flies under the radar even though it affects up to one in six men at some point in their lifetimes.

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Radical prostatectomy changes the experience of orgasm. But it doesn’t need to be any less pleasurable or satisfying, says Dr. Ravi Kacker, a urologist and fellow in male sexual medicine at Harvard-affiliated Beth Israel Deaconess Medical Center.

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New research has has identified an enzyme that may be the escape hatch that advanced prostate cancer uses to evade hormone therapy. If the findings hold up, the enzyme might be a prime target for a drug that would treat castration-resistant prostate cancer.

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Metformin—the drug that millions of people with diabetes take to control their blood sugar—may be on the brink of a second career. Evidence from a variety of studies suggests that metformin may delay or slow the progression of prostate cancer. Metformin does not, however, appear to prevent the development of prostate cancer in the first place.

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Prostate cancer trajectory set early

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In many men diagnosed with prostate cancer, the cancer cells grow so slowly that they never break free of the gland, spread to distant sites, and pose a serious risk to health and longevity. In others, cancer is fast growing and aggressive from the beginning. A new Harvard study shows that the aggressiveness of prostate cancer at diagnosis remains stable over time for most men.

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The omega-3 fats in fish have been linked to all sorts of health benefits, including protection against prostate cancer. But for the second time in two years, researchers have found a link between high levels of omega-3 fats in the blood and prostate cancer. Researchers at the Fred Hutchinson Cancer Center in Seattle men with high levels of omega-3 fats were 43% more likely to have been diagnosed with prostate cancer than men with low levels. The finding were published online in the Journal of the National Cancer Institute.

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The radioactive element radium has been used to treat cancer since soon after its discovery in 1898 by Marie Curie and her husband, Pierre. And it’s still finding new uses—a recently approved form of radium, radium-223 (Xofigo), is now being used to treat prostate cancer that has spread to the bones. Researchers say that Xofigo addresses “an unmet need” in men with this type of prostate cancer, since current therapies don’t work very well against it.

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Is it possible for a gene test to identify whether a prostate that’s healthy today is sure to develop cancer down the road? And should results of such a test be the basis for removing a seemingly healthy prostate gland? Those are questions raised by recent press reports of a British man who had his prostate gland removed because he carried a faulty gene called BRCA2.

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Most men with advanced prostate cancer are at high risk for developing bone metastases, the process by which cancer spreads to and weakens the bones. A serious health and financial concern, bone metastases can lead to fractures, spinal cord compression, pain and a need for radiation therapy or bone surgery. These complications are referred to […]

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